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action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /home2/tyler/public_html/intlhsa.org/wp-includes/functions.php on line 6121After much debate and consideration, IHSA suggests that the minimal amount of hydrogen should be established as a dose per day in a maximal volume of solution. The standard has been determined to provide at least 0.5 mg of H2<\/sub>\u00a0by ingesting a maximal volume of 1 L of product water, or 500 mL of specialty beverages.<\/p>\n It is understood that more research is needed to fully know the minimum effective dose (MED) and the minimum effective concentration (MEC) of H2<\/sub>\u00a0at the cellular level. Ideally, the dose would be given in mg\/kg of body weight with an optimal time factor based on its half-life and pharmacokinetics\/pharmacodynamics. However, this is more challenging with H2<\/sub>\u00a0because, unlike conventional pharmacological agents, H2<\/sub>\u00a0does not have a single\/specific receptor\/target or organ function. The MED\/MEC will likely vary based on factors such as age, body weight, disease, genetics, intestinal bacteria, diet, etc. The IHSA recommendation is simply a standard based on the current cell, animal, and human clinical studies. This standard is subject to change based on additional biomedical research.<\/p>\n<\/div>